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Pentosidine

CAT: 0804-HY-113033Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-113033Size:1 Each
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Description
Pentosidine is an advanced glycation end product (AGE) and cross-linked substance with fluorescent properties. Pentosidine is present in various human tissues and can serve as a biomarker for diabetes, aging, uremia, protein accumulation damage, and non-enzymatic modification of long-lived proteins in the Maillard reaction. It aids in gaining a deeper understanding of the overall role of the Maillard reaction in aging and disease[1][2].
CAS Number
124505-87-9
UNSPSC
12352005
Hazard Statement
H302-H312-H315-H319-H332-H335
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pentosidine.html
Smiles
OC([C@@H](N)CCCCN1C2=NC(NCCC[C@H](N)C(O)=O)=NC2=CC=C1)=O
Molecular Formula
C17H26N6O4
Molecular Weight
378.43
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Sell DR, et al. Pentosidine: a molecular marker for the cumulative damage to proteins in diabetes, aging, and uremia. Diabetes Metab Rev. 1991;7 (4) :239-251.|[2]Requena JR, et al. Measurement of pentosidine in biological samples. Methods Mol Med. 2000;38:209-17.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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