MM 419447

• Description:

  MM 419447, a linaclotide metabolite, is a guanylate cyclase-C agonist. MM 419447 has the potential for the research of the irritable bowel syndrome with constipation (IBS-C) [1].

• UNSPSC:

  12352209

• Target:

  Guanylate Cyclase

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/mm-419447.html

• Purity:

  98.69

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  [CCEYCCNPACTGC(Disulfidebridge:Cys1-Cys6;Cys2-Cys10;Cys5-Cys13)]

• Molecular Formula:

  C50H70N14O19S6

• Molecular Weight:

  1363.56

• References & Citations:

  [1]Busby RW, et al. Pharmacologic properties, metabolism, and disposition of linaclotide, a novel therapeutic peptide approved for the treatment of irritable bowel syndrome with constipation and chronic idiopathic constipation. J Pharmacol Exp Ther. 2013;344 (1) :196-206.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [1092457-78-7]