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(+) -LRH-1 modulator-1

CAT: 0804-HY-147105A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-147105A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(+) -LRH-1 modulator-1 is a stereoisomer of LRH-1 modulator-1. LRH-1 modulator-1 (compound 6N) is a potent LRH-1 (liver receptor homolog-1) modulator/agonist. LRH-1 modulator-1 has anti-inflammatory effects in intestinal organoids. LRH-1 modulator-1 induces the anti-inflammatory cytokine IL-10 and reduces the inflammatory cytokines IL-1b and TNFa[1].
UNSPSC
12352005
Target
Interleukin Related; Orphan Nuclear Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/plus-lrh-1-modulator-1.html
Purity
99.38
Smiles
C=C(C1=CC=CC=C1)[C@]([C@](C2)([H])[C@H]3N[S](N)(=O)=O)(CC3)C(C4=CC=CC=C4)=C2CCCCCC
Molecular Formula
C28H36N2O2S
Molecular Weight
464.66
References & Citations
[1]Mays S G, et al. Development of the first low nanomolar liver receptor homolog-1 agonist through structure-guided design[J]. Journal of medicinal chemistry, 2019, 62 (24) : 11022-11034.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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