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LRH-1 antagonist-1

CAT: 0013-GTR19274345-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19274345-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LRH-1 antagonist-1 (Compound 3d2) is an LRH-1 antagonist with a Kd of 1.8 μM. It inhibits LRH-1 transcriptional activity and reduces G0S2 expression. Additionally, LRH-1 antagonist-1 suppresses the proliferation of LRH-1 positive cancer cells and can be utilized for research in pancreatic, colon, and breast cancers.
CAS Number
1185486-16-1
Smiles
N1=C (N=C (C (=C1C2=CC=CC (=C2) C3=NN (C=C3) CCN (C) C) C) C) N (C) C
Molecular Formula
C21H28N6
Molecular Weight
364.5
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

4-(3-{1-[2-(dimethylamino)ethyl]-1H-pyrazol-3-yl}phenyl)-N,N,5,6-tetramethyl-2-pyrimidinamine
CAS Number1185486-16-1
PubChem CID30876879
IUPAC Name4-[3-[1-[2-(dimethylamino)ethyl]pyrazol-3-yl]phenyl]-N,N,5,6-tetramethylpyrimidin-2-amine
Molecular FormulaC21H28N6
Molecular Weight364.5
XLogP3
Topological Polar Surface Area50.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count27
Formal Charge0
Complexity456
SMILES
CC1=C(N=C(N=C1C2=CC=CC(=C2)C3=NN(C=C3)CCN(C)C)N(C)C)C
InChI
InChI=1S/C21H28N6/c1-15-16(2)22-21(26(5)6)23-20(15)18-9-7-8-17(14-18)19-10-11-27(24-19)13-12-25(3)4/h7-11,14H,12-13H2,1-6H3
InChIKey
SVOZAMOPQXHFML-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(3-{1-[2-(dimethylamino)ethyl]-1H-pyrazol-3-yl}phenyl)-N,N,5,6-tetramethyl-2-pyrimidinamine
CAS: 1185486-16-1
CID: 30876879
Formula: C21H28N6
MW: 364.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight364.5
XLogP33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass364.23754492
Monoisotopic Mass364.23754492
Topological Polar Surface Area50.1 Ų
Heavy Atom Count27
Formal Charge0
Complexity456
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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