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LLO (91-99)

CAT: 0804-HY-P2455-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P2455-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LLO (91-99) (Listeriolysin O (91-99) ) is an exotoxin and class I MHC-restricted T-cell epitope of listeriolysin (LLO) . LLO (91-99) is processed by antigen-presenting cells, binds to MHC class I molecules and is presented to the cell surface. LLO (91-99) induces CTL responses and effectively eliminates Listeria from infected cells. LLO (91-99) can be used in the research of Listeria infections (e.g., listeriosis) [1][2][3].
CAS Number
137856-41-8
Product Name Alternative
Listeriolysin O (91-99)
UNSPSC
12352209
Target
Bacterial
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/llo-91-99.html
Purity
99.24
Solubility
H2O : 50 mg/mL (ultrasonic; warming) |DMSO : ≥ 100 mg/mL
Smiles
O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)CN
Molecular Formula
C47H67N11O17
Molecular Weight
1058.10
References & Citations
[1]N K Verma, et al. Delivery of class I and class II MHC-restricted T-cell epitopes of listeriolysin of Listeria monocytogenes by attenuated Salmonella. Vaccine. 1995 Feb;13 (2) :142-50.|[2]Carrero JA, et al. Listeriolysin o is strongly immunogenic independently of its cytotoxic activity. PLoS One. 2012;7 (3) :e32310. |[3]Calderón-González R, et al. Cellular vaccines in listeriosis: role of the Listeria antigen GAPDH. Front Cell Infect Microbiol. 2014 Feb 21;4:22.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
No Development Reported

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