LLO (91-99)

• Description:

  LLO (91-99) (Listeriolysin O (91-99) ) is an exotoxin and class I MHC-restricted T-cell epitope of listeriolysin (LLO) . LLO (91-99) is processed by antigen-presenting cells, binds to MHC class I molecules and is presented to the cell surface. LLO (91-99) induces CTL responses and effectively eliminates Listeria from infected cells. LLO (91-99) can be used in the research of Listeria infections (e.g., listeriosis) [1][2][3].

• Product Name Alternative:

  Listeriolysin O (91-99)

• UNSPSC:

  12352209

• Target:

  Bacterial

• Type:

  Peptides

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/llo-91-99.html

• Purity:

  99.24

• Solubility:

  H2O : 50 mg/mL (ultrasonic; warming) |DMSO : ≥ 100 mg/mL

• Smiles:

  O=C(N[C@@H](CC1=CC=C(C=C1)O)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(O)=O)=O)=O)=O)=O)=O)=O)=O)CN

• Molecular Formula:

  C47H67N11O17

• Molecular Weight:

  1058.10

• References & Citations:

  [1]N K Verma, et al. Delivery of class I and class II MHC-restricted T-cell epitopes of listeriolysin of Listeria monocytogenes by attenuated Salmonella. Vaccine. 1995 Feb;13 (2) :142-50.|[2]Carrero JA, et al. Listeriolysin o is strongly immunogenic independently of its cytotoxic activity. PLoS One. 2012;7 (3) :e32310. |[3]Calderón-González R, et al. Cellular vaccines in listeriosis: role of the Listeria antigen GAPDH. Front Cell Infect Microbiol. 2014 Feb 21;4:22.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported

• CAS Number:

  [137856-41-8]