T-226296

• UNSPSC Description:

  T-226296 is an oral active and selective melanin-concentrating hormone receptor antagonist with the IC50 values of 5.5 nM and 8.6 nM for human SLC-1 and rat SLC-1, respectively. T-226296 can be used for study of obesity and insulin resistance[1].

• Target Antigen:

  MCHR1 (GPR24)

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/t-226296.html

• Smiles:

  O=C(C1=CC=C(C2=CC=C(C=C2)F)C=C1)NC3=CC=C(CC(CC4)CN(C)C)C4=C3

• Molecular Weight:

  402.50

• References & Citations:

  [1]Takekawa S, et al. T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist. Eur J Pharmacol. 2002;438(3):129-135.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  331758-35-1