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T-226296

CAT: 0804-HY-11085Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-11085Size:1 Each
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Description
T-226296 is an oral active and selective melanin-concentrating hormone receptor antagonist with the IC50 values of 5.5 nM and 8.6 nM for human SLC-1 and rat SLC-1, respectively. T-226296 can be used for study of obesity and insulin resistance[1].
CAS Number
331758-35-1
UNSPSC
12352005
Target
MCHR1 (GPR24)
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/t-226296.html
Smiles
O=C(C1=CC=C(C2=CC=C(C=C2)F)C=C1)NC3=CC=C(CC(CC4)CN(C)C)C4=C3
Molecular Formula
C26H27FN2O
Molecular Weight
402.50
References & Citations
[1]Takekawa S, et al. T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist. Eur J Pharmacol. 2002;438 (3) :129-135.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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