Products for Research Use Only
RegisterLogin

L-2-Hydroxyglutaric acid (Standard)

CAT: 0804-HY-113039RSize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-113039RSize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
L-2-Hydroxyglutaric acid (Standard) is the analytical standard of L-2-Hydroxyglutaric acid. This product is intended for research and analytical applications. L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid can inhibit histone demethylases and hence promote histone methylation[1]. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively[2].
CAS Number
13095-48-2
Product Name Alternative
(S) -2-Hydroxyglutaric acid (Standard)
UNSPSC
12352211
Target
Endogenous Metabolite; Histone Demethylase; Mitochondrial Metabolism; Reference Standards
Type
Reference Standards
Related Pathways
Epigenetics; Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/l-2-hydroxyglutaric-acid-standard.html
Solubility
10 mM in DMSO
Smiles
O=C(O)[C@@H](O)CCC(O)=O
Molecular Formula
C5H8O5
Molecular Weight
148.11
References & Citations
[1]Shim EH, et al. L-2-Hydroxyglutarate: an epigenetic modifier and putative oncometabolite in renal cancer. Cancer Discov. 2014 Nov;4 (11) :1290-8.|[2]da Silva CG, et al. L-2-hydroxyglutaric acid inhibits mitochondrial creatine kinase activity from cerebellum of developing rats. Int J Dev Neurosci. 2003 Jun;21 (4) :217-24.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Clinical Information
No Development Reported

Related Products

CatalogName
HY-W015114R-01L-2-Hydroxyglutaric acid (disodium) (Standard)
HY-113039-01L-2-Hydroxyglutaric acid
HY-W015114-01L-2-Hydroxyglutaric acid (disodium)
HY-113411R3-Hydroxyglutaric acid (Standard)
HY-113038AR-01α-Hydroxyglutaric acid (disodium) (Standard)
HY-W744986-01L-2-Hydroxyglutaric acid-d5 (disodium)
HY-100542R-01D-α-Hydroxyglutaric acid (disodium) (Standard)
HY-113038B-01α-Hydroxyglutaric acid
HY-113038A-01α-Hydroxyglutaric acid (disodium)
HY-113411-013-Hydroxyglutaric acid

Alternative Products

CatalogName
LC-6955.2Hydrochloric acid Standard volumetric solution 2 M (2 N)
LC-5517.2Nitric acid Standard volumetric solution 2 M (2 N)
ICM024 00100MuLi Element Standard Solution For Quality Control Standard 26 - 100mg/L- 7% v/v Nitric Acid /tr Hydrofluoric Acid - 100ppm
ICM025 00100MuLi Element Standard Solution For Quality Control Standard 28 - 100mg/L -5% v/v Nitric Acid /tr Hydrofluoric Acid - 100ppm
ICM023 00100MuLi Element Standard Solution For Quality Control Standard 21 - 100mg/L - 5% v/v Nitric Acid /tr Hydrofluoric Acid - 100ppm
ICM022 00100MuLi Element Standard Solution For Quality Control Standard 19 - 100mg/L - 7% v/v Nitric Acid /tr Hydrofluoric Acid - 100ppm
ICM029 00100MuLi Element Standard Solution For Quality Control Standard 2 -5% v/v Nitric Acid /tr Hydrofluoric Acid
AAS40 00100Platinum AAS Standard 1000 mg/L In 10-20% Hydrochloric Acid Traceable To NIST
LC-6033.1Sulfuric acid Standard volumetric solution 1 M (2 N)
HK200532Acid Phosphatase 2 (ACP2) Human qPCR Template Standard (NM_001610)

Popular Products