SDH-IN-1

• Description:

  SDH-IN-1 (compound 4i) is a succinate dehydrogenase (SDH) inhibitor with an IC50 of 4.53 μM. SDH-IN-1 has potent antifungal activities. SDH-IN-1 displays potent activity against S. sclerotiorum (EC50 of 0.14 mg/L) [1].

• UNSPSC:

  12352005

• Target:

  Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/sdh-in-1.html

• Purity:

  99.95

• Solubility:

  DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles:

  O=C(C1=NN=C(C2=CC=CS2)O1)NCC3=CC=C(Cl)C(Cl)=C3

• Molecular Formula:

  C14H9Cl2N3O2S

• Molecular Weight:

  354.21

• References & Citations:

  [1]Zihui Yang, et al. Design, Synthesis, and Antifungal Activity of Novel Thiophene/Furan-1,3,4-Oxadiazole Carboxamides as Potent Succinate Dehydrogenase Inhibitors. J Agric Food Chem. 2021 Nov 17;69 (45) :13373-13385.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2685795-52-0]