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HERC3 rabbit pAb

CAT: 0855-ES15779-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES15779-01Size:50 µL
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Background
This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
Description
This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012],
UniProt
Q15034
Swiss Prot
Q15034
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human HERC3 AA range: 985-1035
Target
HERC3
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Concentration
1 mg/ml
Dilution
WB 1:500-2000
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm. Cytoplasmic vesicle. Also found in vesicular-like structures.
Gene ID (Human)
8916

UniProtKB · Q15034

Probable E3 ubiquitin-protein ligase HERC3

HERC3_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q15034
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
HERC3
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.3.2.26
Processing
—
Secondary accessions
A8K1S5, Q8IXX3
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmCytoplasmic vesicle

Technical term

Proteomics identificationReference proteome

Domain

Repeat

Molecular function

Transferase

PTM

Ubl conjugation

Biological process

Ubl conjugation pathway

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