Products for Research Use Only
RegisterLogin

RecombinantBMP-3B, Human

CAT: 0384-BK0011-01Size: 10 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0384-BK0011-01Size:10 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Bone Morphogenetic Protein-3B (BMP-3B), also known as Growth/Differentiation Factor 10 (GDF-10), is a cytokine belonging to the Transforming Growth Factor β (TGF-β) superfamily. BMP-3B contains the cystine knot motif shared by other TGF-β family members. BMP-3B was originally identified by PCR based on the BMP-3 sequence, and shares 83% identity with BMP-3. BMP-3B and BMP-2 act as mutual antagonists, as they compete for the availability of signaling protein Smad4. In vivo, BMP-3B is highly expressed in brain, lungs, and bone tissues. The functions of BMP-3B include acting as a dorsaling factor in head development, inhibition of adipogenesis in adipocytes, and induction of bone formation. BMP-3B is down-regulated in lung cancer patient samples, indicating its potential antitumor activity. Recombinant human Bone Morphogenetic Protein-3B (rhBMP-3B) produced in E.coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 111 amino acids each. rhBMP-3B has a molecular mass of 25.1 kDa analyzed by non-reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.
CAS Number
9000-83-3
Endotoxin
< 0.2 EU/μg, determined by LAL method.
Purity
> 95% as analyzed by SDS-PAGE and HPLC.
Reconstitution
Reconstituted in 4mM HCl at 100 μg/mL.
Molecular Weight
25.1 kDa, observed by non-reducing SDS-PAGE.
Storage Conditions
Lyophilized recombinant human Bone Morphogenetic Protein-3B (rhBMP-3B) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhBMP-3B remains stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Appearance
Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation
Lyophilized after extensive dialysis against 4mM HCl.
Host or Source
Escherichia coli.
Recommended Usage
This material is offered by USA Bioworld biotech for research, laboratory or further evaluation purposes. For research use only.
AA Sequence
MQWDEPRVC SRRYLKVDFA DIGWNEWIIS PKSFDAYYCA GACEFPMPKI VRPSNHATIQ SIVRAVGIIP GIPEPCCVPD KMNSLGVLFL DENRNVVLKV YPNMSVDTCA CR

Related Products

CatalogName
BK0010-01RecombinantBMP-2, Human
PPL01954-2aPcDNA3.1 (+) -H3-3B
BK0068-01RecombinantGMF-β, Human
PPL01954-2bPcDNA3.1 (+) -H3-3B (K9R)
PPL01954-2cPcDNA3.1 (+) -H3-3B (T11A)
BK0066-01RecombinantGM-CSF, Human
BK0127-01RecombinantM-CSF, Human
PPL01954-3aPPLK/GFP+Puro-H3-3B shRNA-1
BK0136-01RecombinantMIP-1α/CCL3, Human
BK0125-01RecombinantMCP-1/CCL2, Human

Alternative Products

CatalogName
GTR18991968-01RecombinantBMP-3B, Human
BK0011RecombinantBMP-3B,Human
GTR18991979-01RecombinantBMP-2, Human
BK0010RecombinantBMP-2,Human
OM301677-01MIP 3b Human
QY-E05796Human SEMA 3B
KBH15869GENLISA Human Semaphorin 3B (SEMA-3B / SEMA3B) ELISA
RPU61187-01Human DNA Methyltransferase 3B
24359051IGHD3OR15-3B Adenovirus (Human)
32-6612-20MIP 3b Human, T7

Popular Products