EIF4E Recombinant Rabbit mAb

• Background :

  The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of messenger RNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the 5'-cap structure. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. This gene acts as a proto-oncogene, and its expression and activation is associated with transformation and tumorigenesis. Several pseudogenes of this gene are found on other chromosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

• Structure Composition :

  Store at -20°C. Supplied in 50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

• Product Name Alternative :

  CBP; EIF4F; AUTS19; EIF4E1; eIF-4E; EIF4EL1

• Swiss Prot :

  P06730

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  A synthetic peptide of human eIF4E

• Conjugation :

  Unconjugated

• Applications :

  WB, IHC, ICC/IF, FC, IP

• Purity :

  Affinity Purification

• Modification :

  Unmodification

• Molecular Weight :

  25 kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  IgG

• Applications Notes :

  Western blot detection of eIF4E in C6,3T3 cell lysates using eIF4E antibody (1:1000 diluted) .

• Host or Source :

  Rabbit

• CAS Number :

  9000-83-3