CD354 polyclonal antibody

• Background:

  TREM-1 (triggering receptor expressed on myeloid cells-1) is expressed in monocytes and neutrophils but not in lymphocytes, dendritic cells, or other cell types. TREM-1 is a glycoprotein that is reduced by deglycosylation, in agreement with the predicted molecular mass. TREM-1 is an activating receptor of the Ig superfamily that is expressed on human myeloid cells, selectively expressed on blood neutrophils and a subset of monocytes, and is upregulated by bacterial LPS. Immunoblot analysis shows that TREM-1 is associated with DAP12, a molecule frequently associated with activating receptors. TREM-1 and the myeloid DAP12-associating lectin (MDL-1) are recently identified receptors which associate non-covalently with DAP12 to form receptor complexes that are involved in monocytic activation and inflammatory response.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

• Product Name Alternative:

  Triggering receptor expressed on myeloid cells 1; TREM-1; Triggering receptor expressed on monocytes 1; CD354; TREM1

• Swiss Prot:

  Q9NP99

• Reactivity:

  Human

• Immunogen:

  Synthetic peptide, corresponding to Human CD354.

• Conjugation:

  Unconjugated

• Applications:

  WB IHC

• Dilution:

  WB:1:500~1:1000 IHC:1:50~1:200

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodification

• Molecular Weight:

  ~ 17, 35 kDa

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CD354 polyclonal antibody detects endogenous levels of CD354 protein.

• Applications Notes:

  Western blot (WB) analysis of CD354 polyclonal antibody at 1:500 dilution LaneA:U-87MG whole cell lysate LaneB:A549 whole cell lysate LaneC:L02 whole cell lysate

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4