CD344 polyclonal antibody

• Background:

  This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

• Structure Composition:

  Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.

• Product Name Alternative:

  Fz4; Frizzled-4; Fz-4; FzE4; hFz4; CD344

• Swiss Prot:

  Q9ULV1

• Reactivity:

  Human, Rat, Mouse

• Immunogen:

  Recombinant protein of human CD344.

• Conjugation:

  Unconjugated

• Applications:

  IF

• Dilution:

  IF: 1:100~1:500

• Purity:

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

• Modification:

  Unmodified

• Storage Conditions:

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes:

  For research use only, not for use in diagnostic procedure.

• Specificity:

  CD344 polyclonal antibody detects endogenous levels of CD344 protein.

• Applications Notes:

  Immunofluorescence analysis of MG63 cells using CD344 pAb at dilution of 1:200 (40x lens) .

• Host or Source:

  Rabbit

• CAS Number:

  9007-83-4