HS2ST1 Polyclonal Antibody

CAT: 0384-BS65797-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-BS65797-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Heparan sulfate structures, which are responsible for executing multiple biologic activities, are generated and regulated by heparan sulfate biosynthetic enzymes. HS2ST1 is a 356 amino acid single-pass type II membrane protein that localizes to the golgi apparatus and belongs to the sulfotransferase 3 family. Expressed as multiple alternatively spliced isoforms, HS2ST1 functions to catalyze the transfer of sulfate groups to hexuronic acid residues within maturing heparan sulfate (HS), an event which is crucial for proper HS-related ligand binding and signaling processes. HS2ST1 is subject to post-translational N-glycosylation and, in addition to its role in HS function, may be involved in proper kidney formation.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
2-O-sulfotransferase; 2OST; dJ604K5.2; FLJ11317; heparan sulfate 2 O sulfotransferase 1; Heparan sulfate 2-O-sulfotransferase 1; HS2ST_HUMAN; hs2st1; KIAA0448; MGC131986.
Swiss Prot
Q7LGA3
Reactivity
Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep
Immunogen
KLH conjugated synthetic peptide derived from human HS2ST1:221-320/356
Conjugation
Unconjugated
Applications
WB
Dilution
WB=1:500-2000
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
~52 kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -30°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
HS2ST1 Polyclonal Antibody detects endogenous levels of HS2ST1 protein.
Applications Notes
Primary: Anti-HS2ST1 at 1/300 dilution
Host or Source
Rabbit

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