Mras polyclonal antibody

• Background :

  MRas is a member of the RAS superfamily of GTP-binding proteins which are membrane-anchored, intracellular signal transducers responsible for a variety of normal cellular functions. They are oncogenically activated in a significant fraction of tumors. MRas participates in reorganisation of actin cytoskeleton. It is also involved in focal adhesion and can activate MAPK signalling.

• CAS Number :

  9007-83-4

• Structure Composition :

  0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

• Product Name Alternative :

  M-RAS; M ras; muscle RAS oncogene homolog precursor; Muscle and microspikes Ras; Muscle Ras oncogene homologue; R ras3; R-ras3; Ras related protein MRas; Ras related protein RRas3; RRas3; XRas.

• Swiss Prot :

  O08989

• Reactivity :

  Mouse, Rat

• Immunogen :

  KLH conjugated synthetic peptide derived from mouse MRas:201-259/259

• Conjugation :

  Unconjugated

• Applications :

  WB

• Dilution :

  WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

• Purity :

  Affinity purified by Protein A

• Modification :

  Unmodification

• Molecular Weight :

  ~21kDa

• Storage Conditions :

  Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

• Notes :

  For research use only, not for use in diagnostic procedure.

• Specificity :

  Mras polyclonal Antibody detects endogenous levels of Mras protein.

• Applications Notes :

  Anti-MRas at 1/1000 dilution

• Host or Source :

  Rabbit