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SV2A polyclonal antibody

CAT: 0384-BS65592-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0384-BS65592-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SV2s (Synaptic Vesicle protein 2) are integral membrane glycoproteins present in all synaptic vesicles. They have 12 transmembrane domains predicted by sequence analysis. There are three characterized isoforms, SV2A, SV2B and SV2C. SV2A is expressed ubiquitously throughout the brain. SV2B has a more restricted distribution with varying degrees of coexpression with SV2A. SV2C is more closely related to SV2A but shows a very restricted expression pattern. The highest expression levels were observed in phylogenetically old brain areas like pallidum, the midbrain and the olfactory bulb. SV2A is probably involved in the maintenance of a pool of synaptic vesicles competent for calcium-stimulated exocytosis. SV2A is a highly glycosylated synaptic vesicle protein with homology to transmembrane transporters.
CAS Number
9007-83-4
Structure Composition
0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Product Name Alternative
Synaptic vesicle protein 2A; Synaptic vesicle glycoprotein 2A; Synaptic vesicle protein 2A; Synaptic vesicle protein 2; Sv2; Kiaa0736; SV2A_HUMAN.
Swiss Prot
Q7L0J3
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
Conjugation
Unconjugated
Applications
FCM
Dilution
Flow-Cyt=2ug/Test not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
Purity
Affinity purified by Protein A
Modification
Unmodification
Molecular Weight
~83kDa
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
SV2A polyclonal Antibody detects endogenous levels of SV2A protein.
Host or Source
Rabbit

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