CD81 polyclonal antibody

CAT: 0384-NCP0230P-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0384-NCP0230P-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD81 belongs to the tetraspanin family, which is characterized by four transmembrane domains, one short extracellular domain (ECL1), and one long extracellular domain (ECL2) . Tetraspanins interact with a variety of cell surface proteins and intracellular signaling molecules in specialized tetraspanin enriched microdomains (TEMs) where they mediate a range of processes including adhesion, motility, membrane organization, and signal transduction. CD81, like other tetraspanins, is enriched in exosomes. Many research studies demonstrate a role for CD81 in lymphocyte signaling. CD81 is also a well-characterized receptor for Hepatitis C Virus and facilitates the entry of the virus into target cells.
CAS Number
9007-83-4
Structure Composition
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2.
Product Name Alternative
CD81 antigen; 26 kDa cell surface protein TAPA-1; Target of the antiproliferative antibody 1; Tetraspanin-28 (Tspan-28) ; CD81; TAPA1; TSPAN28
Swiss Prot
P60033
Reactivity
Human, Rat, Mouse
Immunogen
Recombinant protein of human CD81.
Conjugation
Unconjugated
Applications
IF
Dilution
IF: 1:100~1:500
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Modification
Unmodified
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Notes
For research use only, not for use in diagnostic procedure.
Specificity
CD81 polyclonal antibody detects endogenous levels of CD81 protein.
Applications Notes
Immunofluorescence analysis of MG63 cells using CD81 pAb at dilution of 1:200 (40x lens) .
Host or Source
Rabbit

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