RX-37

CAT: 0804-HY-19549Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19549Size:1 Each
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Description
RX-37 is a selective BET inhibitor. RX-37 binds to BET bromodomain proteins (BRD2, BRD3, and BRD4) with Ki values of 3.2-24.7 nM. RX-37 can be used for research of cancers[1].
CAS Number
[1627715-60-9]
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rx-37.html
Solubility
10 mM in DMSO
Smiles
COC1=CC2=C(NC3=C2C(C4=C(C)NN=C4C5CC5)=NC=C3)C=C1C6=C(C)ON=C6C
Molecular Formula
C24H23N5O2
Molecular Weight
413.47
References & Citations
[1]Ran X, et al. Structure-Based Design of γ-Carboline Analogues as Potent and Specific BET Bromodomain Inhibitors. J Med Chem. 2015 Jun 25;58 (12) :4927-39.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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