RX 67668

• Description :

  RX 67668 is a potent cholinesterase inhibitor with an IC50 of 5 μM for both acetylcholinesterase (AChE) and butyrylcholinesterase. RX 67668 can reverse the neuromuscular blockade induced by D-tubocurarine. RX 67668 is a muscle relaxant used to relieve skeletal muscle fatigue[1][2].

• UNSPSC :

  12352005

• Target :

  Cholinesterase (ChE)

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/rx-67668.html

• Solubility :

  10 mM in DMSO

• Smiles :

  [H]Cl.N1([C@H]2[C@@H](C3=CC=CC=C3)CCCC2)CCCC1

• Molecular Formula :

  C16H24ClN

• Molecular Weight :

  265.82

• References & Citations :

  [1]Doxey JC, et al. Some pharmacological properties of RX 67668--a new anticholinesterase. Br J Pharmacol. 1972 Nov;46 (3) :568P-569P.|[2]Metcalf G, wt al. Evaluation of RX 72601 as an anti-curare agent. Br J Anaesth. 1975 Apr;47 (4) :451-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  AChE

• CAS Number :

  [40709-76-0]