RX 336M

• Description :

  RX 336M is a dihydrocodeinone analogue. RX 336M induces behaviors consisting of consisting of behavioral activation, rapid forepaw movements, excessive grooming, and whole body "wet-dog" shakes (WDS) (rapid twisting of the head and trunk with the forepaws leaving the ground) . RX 336M can be used for the study of neurological disease[1][2].

• UNSPSC :

  12352005

• Target :

  Drug Derivative

• Related Pathways :

  Others

• Field of Research :

  Neurological Disease

• Smiles :

  O=C1C2OC3=C(C=CC(CC4C5(C6C1)CCC(C)=C6C)=C3C25CCN4C)OC

• Molecular Formula :

  C24H29NO3

• Molecular Weight :

  379.49

• References & Citations :

  [1]Lee EJ, et al. Discovery of a Novel Potent EGFR Inhibitor Against EGFR Activating Mutations and On-Target Resistance in NSCLC. Clin Cancer Res. 2024 Apr 15;30 (8) :1582-1594. |[2]Isaacson RL, et al. Age- and sex-related induction of excessive grooming and "wet-dog" shakes by the codeinone RX 336-M in the rat. Behav Neural Biol. 1987 May;47 (3) :250-61.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [6701-66-2]