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IVMT-Rx-3

CAT: 0804-HY-156247Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-156247Size:1 Each
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Description
IVMT-Rx-3 is a inhibitor of SDCBP targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin. IVMT-Rx-3 blocks MDA-9/Syntenin interaction with Src, reduces NF-κB activation, and inhibits MMP-2/MMP-9 expression. IVMT-Rx-3 inhibits Melanoma Metastasis[1]
UNSPSC
12352005
Target
MMP; NF-κB; SDCBP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; NF-κB; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ivmt-rx-3.html
Solubility
10 mM in DMSO
Smiles
O=C(O)C(F)(F)F.O=C1N2N=C(N=C2NC3=C1CCC3)C(NC4=C(C=C(C(C)=C4)NC(CCOCCOCCOCCOCCOCCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C(C)C)=O)CC5=CC=C(C=C5)O)=O)CC6=CC=C(O)C=C6)=O)CCC(O)=O)=O)CC(N)=O)=O)[C@@H](C)O)=O)=O)C)=O
Molecular Formula
C69H90F3N13O24
Molecular Weight
1542.52
References & Citations
[1]Pradhan AK, et al. Dual Targeting of the PDZ1 and PDZ2 Domains of MDA-9/Syntenin Inhibits Melanoma Metastasis. Mol Cancer Ther. 2023;22 (10) :1115-1127.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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