Products for Research Use Only
RegisterLogin

ONO-3307

CAT: 0804-HY-19101-03Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-19101-03Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ONO-3307 is a protease inhibitor that competitively inhibits a variety of proteases including trypsin, thrombin, plasma kallikrein, plasmin, pancreatic kallikrein, and chymotrypsin. ONO-3307 alleviates endotoxin-induced experimental disseminated intravascular coagulation (DIC) in rats. ONO-3307 can be used in the study of thrombosis and protease-mediated diseases[1][2].
CAS Number
76472-29-2
UNSPSC
12352005
Target
Kallikrein
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ono-3307.html
Solubility
10 mM in DMSO
Smiles
O=C(OC1=CC=C(S(=O)(N)=O)C=C1)C2=CC=C(NC(N)=N)C=C2.CS(=O)(O)=O
Molecular Formula
C15H18N4O7S2
Molecular Weight
430.46
References & Citations
[1]Yoshikawa T, et al. Protective effects of ONO-3307, a new synthetic protease inhibitor against experimental disseminated intravascular coagulation in rats. Thromb Res. 1990 Oct 1;60 (1) :1-7.|[2]Matsuoka S, et al. Inhibitory effects of ONO-3307 on various proteases and tissue thromboplastin in vitro and on experimental thrombosis in vivo. Jpn J Pharmacol. 1989 Dec;51 (4) :455-63.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Chemical Information

4-Sulfamoylphenyl 4-guanidinobenzoate methanesulfonate
CAS Number76472-29-2
PubChem CID10342645
IUPAC Namemethanesulfonic acid;(4-sulfamoylphenyl) 4-(diaminomethylideneamino)benzoate
Molecular FormulaC15H18N4O7S2
Molecular Weight430.5
Topological Polar Surface Area222
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Heavy Atom Count28
Formal Charge0
Complexity630
SMILES
CS(=O)(=O)O.C1=CC(=CC=C1C(=O)OC2=CC=C(C=C2)S(=O)(=O)N)N=C(N)N
InChI
InChI=1S/C14H14N4O4S.CH4O3S/c15-14(16)18-10-3-1-9(2-4-10)13(19)22-11-5-7-12(8-6-11)23(17,20)21;1-5(2,3)4/h1-8H,(H4,15,16,18)(H2,17,20,21);1H3,(H,2,3,4)
InChIKey
OSILTPUZIFPGFS-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-Sulfamoylphenyl 4-guanidinobenzoate methanesulfonate
CAS: 76472-29-2
CID: 10342645
Formula: C15H18N4O7S2
MW: 430.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight430.5
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass430.06169127
Monoisotopic Mass430.06169127
Topological Polar Surface Area222 Ų
Heavy Atom Count28
Formal Charge0
Complexity630
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-179004ONO-9517601
HY-117444-01ONO-9780307
HY-112788-01ONO-8590580
HY-123816ONO 2050297
HY-150204-01ONO-0740556
HY-164517ONO-7579
HY-123542ONO-3403
HY-114841-01ONO 207
HY-113635ONO-6240
HY-106961-01ONO 1301

Alternative Products

CatalogName
BUP03233-01Ono-3307 mesylate
GTR19211219-01Ono 3307 Free Base
BA8174-10ONO-8430506
C3901-10ONO-8711
BA6672-25ONO-8590580
BA5469-5ONO-0740556
C5743-5ONO-8130
BA5478-1ONO-0300302
B7676-10ONO 2506
B7818-25ONO-7300243

Popular Products