Tyk2-IN-9

Tyk2-IN-9

• CAS Number: 2694816-85-6
• UNSPSC Description: Tyk2-IN-9 (Compound 26) is a selective Tyk-2 inhibitor with IC50s of 0.076 and 1.8 nM for TYK2-JH2 and JAK1-JH2, respectively. Tyk2-IN-9 can be used for the research of inflammatory or autoimmune disease[1].
• Target Antigen: JAK
• Type: Reference compound
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Applications: COVID-19-immunoregulation
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/tyk2-in-9-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=NN=C(NC(C2CC2)=O)C=C1NC3=NN4C=C(N5CC(C(C)O)C5)C=CC4=N3)NC
• Molecular Weight: 451.48
• References & Citations: [1]Qiuwen WANG, et al. Tyk-2 inhibitor. WO2021170046A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported