Timolol (hemihydrate)

• Description :

  Timolol (hemihydrate) is a β-blocker available for both topical and systemic administration. Timolol (hemihydrate) is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension and Timolol (hemihydrate) also has cardioprotective effect[1][2].

• Product Name Alternative :

  (S) -L-714,465 (hemihydrate) ; MK 950 (hemihydrate)

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/timolol-hemihydrate.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O[C@@H](CNC(C)(C)C)COC1=NSN=C1N2CCOCC2.[1/2H2O]

• Molecular Formula :

  C13H24N4O3S.1/2H2O

• Molecular Weight :

  325.43

• References & Citations :

  [1]Figen Amber Cicek, et al. Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress. J Bioenerg Biomembr|[2]E. Ansari, et al. Treatment of open-angle glaucoma and ocular hypertension with preservative-free tafuprost/timolol fxed-dose combination therapy: 6 case reports and clinical outcomes. BMC Ophthalmol. 2022 Apr 2;22 (1) :152.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Isoform :

  β adrenergic receptor

• CAS Number :

  [91524-16-2]