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Timolol (hemihydrate)

CAT: 0804-HY-17494ASize: 1 EachDry Ice: NoHazardous: No
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Description
Timolol (hemihydrate) is a β-blocker available for both topical and systemic administration. Timolol (hemihydrate) is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension and Timolol (hemihydrate) also has cardioprotective effect[1][2].
CAS Number
91524-16-2
Product Name Alternative
(S) -L-714,465 (hemihydrate) ; MK 950 (hemihydrate)
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Cancer
Assay Protocol
https://www.medchemexpress.com/timolol-hemihydrate.html
Solubility
10 mM in DMSO
Smiles
O[C@@H](CNC(C)(C)C)COC1=NSN=C1N2CCOCC2.[1/2H2O]
Molecular Formula
C13H24N4O3S.1/2H2O
Molecular Weight
325.43
References & Citations
[1]Figen Amber Cicek, et al. Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress. J Bioenerg Biomembr|[2]E. Ansari, et al. Treatment of open-angle glaucoma and ocular hypertension with preservative-free tafuprost/timolol fxed-dose combination therapy: 6 case reports and clinical outcomes. BMC Ophthalmol. 2022 Apr 2;22 (1) :152.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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