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Timolol

CAT: 0804-HY-17494Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-17494Size:1 Each
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Description
Timolol is a β-blocker available for both topical and systemic administration. Topical Timolol is primarily used to reduce intraocular pressure with open-angle glaucoma and ocular hypertension. Timolol can also be used for the research of infantile hemangiomas, hypertension, myocardial infarction, migraine prophylaxis, and atrial fibrillation.Timolol also has cardioprotective effect[1][2].
CAS Number
26839-75-8
Product Name Alternative
(S) -L-714,465; MK 950 (free base)
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Cardiovascular Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/timolol.html
Solubility
10 mM in DMSO
Smiles
O[C@H](COC1=NSN=C1N2CCOCC2)CNC(C)(C)C
Molecular Formula
C13H24N4O3S
Molecular Weight
316.42
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]James Barnes; Majid Moshirfar. Timolol.|[2]E. Ansari, et al. Treatment of open-angle glaucoma and ocular hypertension with preservative-free tafuprost/timolol fxed-dose combination therapy: 6 case reports and clinical outcomes. BMC Ophthalmol. 2022 Apr 2;22 (1) :152.|[3]Figen Amber Cicek, et al. Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress. J Bioenerg Biomembr. 2014 Oct;46 (5) :377-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor
Citation 01
Patent. US20230090708A1.|Redox Biol. 2024 Dec 21:79:103481.|Adv Mater. 2025 Jan 6:e2419306.|Mater Today Bio. 2025 Apr 12:32:101752.|Protein Cell. 2019 Mar;10 (3) :178-195.

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