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Esomeprazole (hemistrontium)

CAT: 0804-HY-17021CSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-17021CSize:1 Each
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Description
Esomeprazole ((S) -Omeprazole) hemistrontium is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole hemistrontium has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].
CAS Number
914613-86-8
Product Name Alternative
(S) -Omeprazole (hemistrontium) ; (-) -Omeprazole (hemistrontium)
UNSPSC
12352100
Target
Bacterial; Proton Pump
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Cancer; Endocrinology; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/esomeprazole-hemistrontium.html
Solubility
10 mM in DMSO
Smiles
O=[S@](C1=NC2=CC=C(OC)C=C2[N-]1)CC3=NC=C(C)C(OC)=C3C.[1/2].[Sr+2]
Molecular Formula
C17H18N3O3S.1/2Sr
Molecular Weight
388.22
References & Citations
[1]Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17 (3) :439-46.|[2]Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16.|[3]Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59 (14) :1333-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched

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