(R) -Esomeprazole

• Description :

  (R) -Esomeprazole ((R) -Omeprazole; (+) -Omeprazole) is an orally active cytochrome P450 2C19, CYP3A4, and CYP2C9-related metabolic modulator. (R) -Esomeprazole can be used in studies of digestive system diseases and compound metabolic interactions[1][2].

• Product Name Alternative :

  (R) -Omeprazole; (+) -Omeprazole

• UNSPSC :

  12352005

• Hazard Statement :

  H315-H319-H335

• Target :

  Cytochrome P450

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Inflammation/Immunology; Metabolic Disease

• Smiles :

  O=[S@@](C1=NC2=CC(OC)=CC=C2N1)CC3=NC=C(C)C(OC)=C3C

• Molecular Formula :

  C17H19N3O3S

• Molecular Weight :

  345.42

• Precautions :

  P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

• References & Citations :

  [1]Pippa LF, et al. Impact of obesity and roux-en-Y gastric bypass on the pharmacokinetics of (R) - and (S) -omeprazole and intragastric pH. CPT Pharmacometrics Syst Pharmacol. 2024 Sep;13 (9) :1528-1541. |[2]Niwa T, et al. Stereoselectivity of human cytochrome p450 in metabolic and inhibitory activities. Curr Drug Metab. 2011 Jul;12 (6) :549-69.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound2

• Clinical Information :

  No Development Reported

• CAS Number :

  [119141-89-8]