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(R) -Esomeprazole

CAT: 0804-HY-Z2667Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-Z2667Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -Esomeprazole ((R) -Omeprazole; (+) -Omeprazole) is an orally active cytochrome P450 2C19, CYP3A4, and CYP2C9-related metabolic modulator. (R) -Esomeprazole can be used in studies of digestive system diseases and compound metabolic interactions[1][2].
CAS Number
119141-89-8
Product Name Alternative
(R) -Omeprazole; (+) -Omeprazole
UNSPSC
12352005
Hazard Statement
H315-H319-H335
Target
Cytochrome P450
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Inflammation/Immunology; Metabolic Disease
Smiles
O=[S@@](C1=NC2=CC(OC)=CC=C2N1)CC3=NC=C(C)C(OC)=C3C
Molecular Formula
C17H19N3O3S
Molecular Weight
345.42
Precautions
P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
References & Citations
[1]Pippa LF, et al. Impact of obesity and roux-en-Y gastric bypass on the pharmacokinetics of (R) - and (S) -omeprazole and intragastric pH. CPT Pharmacometrics Syst Pharmacol. 2024 Sep;13 (9) :1528-1541. |[2]Niwa T, et al. Stereoselectivity of human cytochrome p450 in metabolic and inhibitory activities. Curr Drug Metab. 2011 Jul;12 (6) :549-69.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
No Development Reported

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