Esomeprazole

• Description :

  Esomeprazole ((S) -Omeprazole) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole has the potential for symptomatic gastroesophageal reflux disease research[1][2][3].

• Product Name Alternative :

  (S) -Omeprazole; (-) -Omeprazole

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Bacterial; Proton Pump

• Type :

  Reference compound

• Related Pathways :

  Anti-infection; Membrane Transporter/Ion Channel

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Cancer; Endocrinology; Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/esomeprazole.html

• Purity :

  99.46

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  O=[S@](C1=NC2=CC=C(OC)C=C2N1)CC3=NC=C(C)C(OC)=C3C

• Molecular Formula :

  C17H19N3O3S

• Molecular Weight :

  345.42

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Wayne Goh, et al. Use of proton pump inhibitors as adjunct treatment for triple-negative breast cancers. An introductory study. J Pharm Pharm Sci. 2014;17 (3) :439-46.|[2]Christina Nelson, et al. Therapeutic Efficacy of Esomeprazole in Cotton Smoke-Induced Lung Injury Model. Front Pharmacol. 2017 Jan 26;8:16.|[3]Thomas J Johnson, et al. Esomeprazole: a clinical review. Am J Health Syst Pharm. 2002 Jul 15;59 (14) :1333-9.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• Citation 01 :

  Int Immunopharmacol. 2025 Aug 13:164:115367.|Chem Eng J. 2024 Dec 1.|SSRN. 2025 Aug 20.

• CAS Number :

  [119141-88-7]