AM-5262

CAT: 0804-HY-16619Size: 1 EachDry Ice: NoHazardous: No
HY-166191 Each
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AM-5262 is a GPR40 full agonist with an EC50 value of 0.081 μM. AM-5262 can be used for the research of type II diabetes[1].
CAS Number
[1222088-90-5]
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/am-5262.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(F)C(C2=C([C@@H]3CCCC3(C)C)C=C(COC4=CC=C(CC[C@]56C[C@]6(C(O)=O)[H])C5=C4)C=C2)=C1
Molecular Formula
C33H35FO4
Molecular Weight
514.63
References & Citations
[1]Wang Y, et al. Discovery and Optimization of Potent GPR40 Full Agonists Containing Tricyclic Spirocycles. ACS Med Chem Lett. 2013;4 (6) :551-555. Published 2013 May 7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported