AM-4668

CAT: 0804-HY-12585-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-12585-01Size:5 mg
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Description
AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively[1].
CAS Number
[1011531-27-3]
UNSPSC
12352005
Target
Free Fatty Acid Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/am-4668.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
OC(C[C@H](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O
Molecular Formula
C24H19F3N2O4S
Molecular Weight
488.48
References & Citations
[1]Liu JJ, et al. Optimization of GPR40 Agonists for Type 2 Diabetes. ACS Med Chem Lett. 2014 Feb 6;5 (5) :517-21.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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