PCSK9-IN-24

• UNSPSC Description:

  PCSK9-IN-24 (Compound OY3) is a compound that targets PCSK9. PCSK9-IN-24 reduces PCSK9 levels and increases LDL uptake and may be used in atherosclerosis research[1].

• Target Antigen:

  PCSK9

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/pcsk9-in-24.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC2=C(C=C1OCCCCN(C3=C/4C=C(C=C3)Br)C(C4=C/C5=CC(OC)=C(C(Br)=C5)O)=O)C(CC(NC6=NC=CS6)=O)(C)NCC2

• Molecular Weight:

  812.57

• References & Citations:

  [1]Ouyang Z, et al. Targeted Degradation of PCSK9 In Vivo by Autophagy-Tethering Compounds. J Med Chem. 2024 Jan 11;67(1):433-449.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2974496-96-1