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TLR7 agonist 19

CAT: 0804-HY-162163Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162163Size:1 Each
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Description
TLR7 agonist 19 (Compound 14) is a Toll-like receptor 7 (TLR7) agonist with excellent pharmacokinetic properties and synergistic antitumor activity.
CAS Number
2682008-42-8
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tlr7-agonist-19.html
Solubility
10 mM in DMSO
Smiles
CCC[C@H](NC1=C(N(CC2=NC=C(C3CCN(C4CCOCC4)CC3)C=C2OC)N=C5)C5=NC(N)=N1)CCO
Molecular Formula
C28H42N8O3
Molecular Weight
538.68
References & Citations
[1]He L, et al. Identification and Optimization of Small Molecule Pyrazolopyrimidine TLR7 Agonists for Applications in Immuno-oncology[J]. ACS Medicinal Chemistry Letters, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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