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TLR7 agonist 3

CAT: 0804-HY-117602-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-117602-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TLR7 agonist 3 (compound 2) is a TLR7 agonist. TLR7 agonist 3 (compound 5) can be coupled to folate receptor binding ligands to target myeloid-derived suppressor cells and exert anticancer activity[1][2].
CAS Number
1229024-78-5
UNSPSC
12352005
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tlr7-agonist-3.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic) |Ethanol : ≥ 50 mg/mL
Smiles
CC(O)(C)CN1C(CCCC)=NC2=C1C3=CC=CC=C3N=C2N
Molecular Formula
C18H24N4O
Molecular Weight
312.41
References & Citations
[1]Urban Švajger, et al. New antagonists of toll-like receptor 7 discovered through 3D ligand-based virtual screening. Medicinal Chemistry Research. 2015. 24: 362-371.|[2]Method of treating cancer by targeting myeloid-derived suppressor cells comprising a folate receptor binding ligand attached to a drug via a linker. World Intellectual Property Organization, WO2017205661 A1 2017-11-30.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TLR7

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