PPARγ agonist 7

CAT: 0804-HY-147511Size: 1 EachDry Ice: NoHazardous: No

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Description

PPARγ agonist 7 (Compound 3a) is a potent and selective agonist of PPARγ. PPARγ agonist 7 promotes adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs) as a novel PPARγ full agonist (EC50, 4.34 μM) [1].

CAS Number

2569295-93-6

UNSPSC

12352005

Target

PPAR

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pparγ-agonist-7.html

Solubility

10 mM in DMSO

Smiles

C[C@@H]1OC(/C([C@@H]1O)=C/CCCCCCCC/C=C2C(O[C@H]([C@H]/2O)C)=O)=O

Molecular Formula

C20H30O6

Molecular Weight

366.45

References & Citations

[1]Ahn S, et al. Novel linked butanolide dimer compounds increase adiponectin production during adipogenesis in human mesenchymal stem cells through peroxisome proliferator-activated receptor γ modulation. Eur J Med Chem. 2020 Feb 1;187:111969.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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PPARγ agonist 7

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