T-1-MBHEPA

CAT: 0804-HY-162064Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-162064Size:1 Each

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Description

T-1-MBHEPA is a potent inhibitor of VEGFR-2, with the IC50 value of 0.121±0.051 μM. T-1-MBHEPA has anti-tumor and anti-angiogenic effect[1].

UNSPSC

12352005

Target

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/t-1-mbhepa.html

Solubility

10 mM in DMSO

Smiles

O=C(C(N(C)C=N1)=C1N2C)N(CC(NC3=CC=C(/C(C)=N/NC(C4=CC=CC(C)=C4)=O)C=C3)=O)C2=O

Molecular Formula

C25H25N7O4

Molecular Weight

487.51

References & Citations

[1]Ibrahim H Eissa, et al. Computer-assisted drug discovery (CADD) of an anti-cancer derivative of the theobromine alkaloid inhibiting VEGFR-2. Saudi Pharm J. 2023 Dec;31 (12) :101852.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

VEGFR2/KDR/Flk-1

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