T-1-MCPAB

CAT: 0804-HY-156452Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-156452Size:1 Each

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Description

T-1-MCPAB is a VEGFR-2 inhibitor (IC50=0.135 µM) that effectively inhibits MCF7 migration. T-1-MCPAB can be used in cancer research[1].

UNSPSC

12352005

Target

VEGFR

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/t-1-mcpab.html

Solubility

10 mM in DMSO

Smiles

CN(C(N1CC(NC2=CC=C(C(NC3=CC=CC(Cl)=C3)=O)C=C2)=O)=O)C(N=CN4C)=C4C1=O

Molecular Formula

C22H19ClN6O4

Molecular Weight

466.88

References & Citations

[1]Eissa IH, et al. Anti-breast cancer potential of a new xanthine derivative: In silico, antiproliferative, selectivity, VEGFR-2 inhibition, apoptosis induction and migration inhibition studies. Pathol Res Pract. 2023 Nov;251:154894.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

VEGFR2/KDR/Flk-1

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