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MMT3-72-M2

CAT: 0804-HY-162031Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162031Size:1 Each
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Description
MMT3-72-M2 is an MMT3-72 metabolite. MMT3-72-M2 is a selective JAK1 inhibitor. MMT3-72-M2 inhibits JAK1, JAK2, TYK2, and JAK3 with IC50 values of 10.8 nM, 26.3 nM, 91.6 nM, 328.7 nM, respectlly[1].
CAS Number
936091-74-6
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/mmt3-72-m2.html
Solubility
10 mM in DMSO
Smiles
O=S(C1=CC=CC(NC2=NC(NC3=CC=C(OCCO)C=C3)=NC=C2C)=C1)(NC(C)(C)C)=O
Molecular Formula
C23H29N5O4S
Molecular Weight
471.57
References & Citations
[1]Yingzi Bu, et al. A gastrointestinal locally activating Janus kinase inhibitor to treat ulcerative colitis. J Biol Chem. 2023, 299, 2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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