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S-72

CAT: 0804-HY-156958-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-156958-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
S-72 inhibits tubulin polymerization and further triggers mitosis-phase cell cycle arrest and cell apoptosis, in addition to suppressing STAT3 signaling[1].
CAS Number
2446799-14-8
UNSPSC
12352005
Target
Apoptosis; Microtubule/Tubulin; Mitosis; STAT
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Cytoskeleton; JAK/STAT Signaling; Stem Cell/Wnt
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/s-72.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C(C)C(NS(=O)(C2=CC=C(C)C=C2)=O)=C1)NCC3=CN(C)N=C3
Molecular Formula
C20H22N4O3S
Molecular Weight
398.48
References & Citations
[1]Zhenyan Hou, et al. S-72, a Novel Orally Available Tubulin Inhibitor, Overcomes Paclitaxel Resistance via Inactivation of the STING Pathway in Breast Cancer. Pharmaceuticals (Basel) . 2023 May 15;16 (5) :749.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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