NT-B2R

• UNSPSC Description:

  NT-B2R is a potent MYC inhibitor. NT-B2R inhibited MYC transcriptional activity and cell proliferation[1].

• Target Antigen:

  c-Myc

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nt-b2r.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(OC/C=C/[C@H]1CC2[C@@H](/C=C/COC(CC[C@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCCCNC2=O)NC([C@H](CCCNC(N)=N)NC([C@H](CC3=CNC=N3)NC([C@H]4N(C([C@@H](N5)CC6=CNC7=C6C=CC=C7)=O)CCC4)=O)=O)=O)=O)=O)CC(C)C)=O)C(N)=O)=O)C1)CC[C@H](N)C5=O

• Molecular Weight:

  1421.65

• References & Citations:

  [1]Li Z, et al. MYC-Targeting Inhibitors Generated from a Stereodiversified Bicyclic Peptide Library. J Am Chem Soc. 2024 Jan 17;146(2):1356-1363.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported