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WDR5-IN-8

CAT: 0804-HY-161123Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161123Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
WDR5-IN-8 is a WDR5 inhibitor with IC50 value of 15.5 nM. WDR5-IN-8 shows good anti-proliferative activity in two human acute leukemia cell lines. WDR5-IN-8 has antitumor activity[1].
UNSPSC
12352005
Target
WDR5
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wdr5-in-8.html
Solubility
10 mM in DMSO
Smiles
CC1=C(C2=C(C3=CC(NCC4=C(NC=N4)C)=C2)CCN(C3=O)CC5=CC=C(C=C5)Cl)C=C(CO)C=C1
Molecular Formula
C29H29ClN4O2
Molecular Weight
501.02
References & Citations
[1]Qin S, et al. Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach. J Med Chem. 2024 Jan 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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