WDR5-IN-8

• UNSPSC Description:

  WDR5-IN-8 is a WDR5 inhibitor with IC50 value of 15.5 nM. WDR5-IN-8 shows good anti-proliferative activity in two human acute leukemia cell lines. WDR5-IN-8 has antitumor activity[1].

• Target Antigen:

  WDR5

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/wdr5-in-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=C(C2=C(C3=CC(NCC4=C(NC=N4)C)=C2)CCN(C3=O)CC5=CC=C(C=C5)Cl)C=C(CO)C=C1

• Molecular Weight:

  501.02

• References & Citations:

  [1]Qin S, et al. Discovery and Optimization of WDR5 Inhibitors via Cascade Deoxyribonucleic Acid-Encoded Library Selection Approach. J Med Chem. 2024 Jan 3.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported