WDR5-IN-5

CAT: 0804-HY-150654-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-150654-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
WDR5-IN-5 is an orally active and selective inhibitor of WIN site of WD repeat domain 5 (WDR5) . WDR5-IN-5 exhibits anti-proliferative activity towards cancer cells and good pharmacokinetics profile in mice. WDR5-IN-5 shows high affinity to WDR5 and the binding affinity Ki value [1].
CAS Number
[2417012-26-9]
UNSPSC
12352005
Target
WDR5
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/wdr5-in-5.html
Purity
99.56
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1N([C@@H](C2CC2)C3=NC=CC(C)=C3)CCC4=C1C=C(CN5C=CN=C5)C=C4C6=CN(CC)N=C6C(F)(F)F
Molecular Formula
C29H29F3N6O
Molecular Weight
534.58
References & Citations
[1]Teuscher KB, et al. Discovery of Potent Orally Bioavailable WD Repeat Domain 5 (WDR5) Inhibitors Using a Pharmacophore-Based Optimization. J Med Chem. 2022 Apr 28. 65 (8) :6287-6312.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-161123WDR5-IN-8
HY-154949-01WDR5-IN-6
HY-133121-01WDR5-IN-1
HY-157332WDR5-IN-7
HY-19347-01WDR5-0103
HY-148817-01WDR5-0102
HY-P703615-01WDR5, Human
HY-111753-01WDR5-IN-4
HY-111753A-01WDR5-IN-4 (TFA)
HY-168488WDR5 ligand 2

Alternative Products

CatalogName
BA4836-5WDR5-IN-5
bs-60233C-01WDR5-0103 --- WDR5 Inhibitor
MBS8566037-01WDR5
abx116661Wd Repeat Domain 5 (WDR5) Antibody
bsm-61682R-Cy5.5WDR5 Recombinant Antibody, Cy5.5 Conjugated
339696-01WD repeat-containing Protein 5 (WDR5)
MBS7126727-01WDR5 Antibody
5323/50WDR5 0103

Popular Products