WDR5 ligand 2

• Description :

  WDR5 ligand 2 is the ligand for WDR5 and can be used for synthesis of PROTAC WDR5 degrader 1 (HY-168487) [1].

• UNSPSC :

  12352005

• Target :

  Ligands for Target Protein for PROTAC; WDR5

• Related Pathways :

  Epigenetics; PROTAC

• Field of Research :

  Cancer

• Smiles :

  O=C(C(C(C(F)(F)F)=C1)=CNC1=O)NC2=C(N3CCN(CC3)C)C=CC(C4=CC=C(C=C4)C(OC(C)(C)C)=O)=C2

• Molecular Formula :

  C29H31F3N4O4

• Molecular Weight :

  556.58

• References & Citations :

  [1]Dölle A, et al., Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. J Med Chem. 2021 Aug 12;64 (15) :10682-10710.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2737222-78-3]