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WDR5 ligand 2

CAT: 0804-HY-168488Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168488Size:1 Each
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Description
WDR5 ligand 2 is the ligand for WDR5 and can be used for synthesis of PROTAC WDR5 degrader 1.
CAS Number
2737222-78-3
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; WDR5
Related Pathways
Epigenetics; PROTAC
Field of Research
Cancer
Smiles
O=C(C(C(C(F)(F)F)=C1)=CNC1=O)NC2=C(N3CCN(CC3)C)C=CC(C4=CC=C(C=C4)C(OC(C)(C)C)=O)=C2
Molecular Formula
C29H31F3N4O4
Molecular Weight
556.58
References & Citations
[1]Dölle A, et al., Design, Synthesis, and Evaluation of WD-Repeat-Containing Protein 5 (WDR5) Degraders. J Med Chem. 2021 Aug 12;64 (15) :10682-10710.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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