WDR5-IN-7

• UNSPSC Description:

  WDR5-IN-7 (Compound 22) is an orally bioavailable benzoxazepinone-based WD repeat domain 5 (WDR5) inhibitor. WDR5-IN-7 can be used for the research of anti-cancer[1].

• Target Antigen:

  Histone Methyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/wdr5-in-7.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1C2=C(OCCN1[C@@H]3C4=CC(OC)=CN=C4CCC3)C(C5=CN(C)N=C5C(F)(F)F)=CC(CN6C=NC=C6)=C2

• Molecular Weight:

  552.55

• References & Citations:

  [1]Teuscher KB, et al. Structure-Based Discovery of Potent, Orally Bioavailable Benzoxazepinone-Based WD Repeat Domain 5 Inhibitors. J Med Chem. 2023 Dec 12.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3032761-31-9