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NLRP3-IN-27

CAT: 0804-HY-161120Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161120Size:1 Each
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Description
NLRP3-IN-27 is a selective NLRP3 inhibitor with a IC50 value of 0.55 μM. NLRP3-IN-27 can be used in the study of inflammation and immunity[1].
CAS Number
2997864-57-8
UNSPSC
12352005
Target
NOD-like Receptor (NLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nlrp3-in-27.html
Solubility
10 mM in DMSO
Smiles
ClC1=CC(CN2C=C(N=N2)C3=CC=C(C=C3)C(OC)=O)=C(C=C1)OC
Molecular Formula
C18H16ClN3O3
Molecular Weight
357.79
References & Citations
[1]Xu Y, et al. Design and Discovery of Novel NLRP3 Inhibitors and PET Imaging Radiotracers Based on a 1,2,3-Triazole-Bearing Scaffold. J Med Chem. 2024 Jan 11;67 (1) :555-571.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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