Aβ42-IN-4

Aβ42-IN-4

• CAS Number: 2387822-02-6
• UNSPSC Description: Aβ42-IN-4 (compound 0043) degrades amyloid precursor protein (APP) and reduces Aβ42 production[1].
• Target Antigen: Amyloid-β
• Type: Reference compound
• Related Pathways: Neuronal Signaling
• Applications: Neuroscience-Neurodegeneration
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/aβ42-in-4.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C1=CC=C2C(SC(NC(NC3=CC(C#N)=CC=C3)=O)=N2)=C1)N4CCOCC4
• Molecular Weight: 407.45
• References & Citations: [1]Sunghan Jung, et al. Small-molecule degraders reduce Aβ production through CAPRIN1-mediated lysosomal degradation of APP in Alzheimer’s iPSC-derived neurons. In preprint.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported