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Aβ42-IN-4

CAT: 0804-HY-161109Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-161109Size:1 Each
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Description
Aβ42-IN-4 (compound 0043) degrades amyloid precursor protein (APP) and reduces Aβ42 production[1].
CAS Number
2387822-02-6
UNSPSC
12352005
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aβ42-in-4.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C2C(SC(NC(NC3=CC(C#N)=CC=C3)=O)=N2)=C1)N4CCOCC4
Molecular Formula
C20H17N5O3S
Molecular Weight
407.45
References & Citations
[1]Sunghan Jung, et al. Small-molecule degraders reduce Aβ production through CAPRIN1-mediated lysosomal degradation of APP in Alzheimer’s iPSC-derived neurons. In preprint.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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