[Ru(phen)2(xant)] (hexafluorophosphate)

• UNSPSC Description:

  [Ru(phen)2(xant)] hexafluorophosphate is an inducer of Autophagy. [Ru(phen)2(xant)] hexafluorophosphate eliminates CRC stem cells by targeting the chaperone Hsp90. [Ru(phen)2(xant)] hexafluorophosphate reduces cell migration and invasion[1].

• Target Antigen:

  Autophagy

• Type:

  Reference compound

• Related Pathways:

  Autophagy

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/ru-phen-2-xant-hexafluorophosphate.html

• Solubility:

  10 mM in DMSO

• Smiles:

  COC1=CC([O-][Ru+2]23([N]4=CC=CC5=C4C6=C(C=CC=[N]62)C=C5)([N]7=CC=CC8=C7C([N]3=CC=C9)=C9C=C8)O=C%10C)=C%10C(OC)=C1.F[P-](F)(F)(F)(F)F

• Molecular Weight:

  801.64

• References & Citations:

  [1]Santos LS, et al. New ruthenium-xanthoxylin complex eliminates colorectal cancer stem cells by targeting the heat shock protein 90 chaperone. Cell Death Dis. 2023 Dec 15;14(12):832.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported