RU-TRAAK-2

• Description :

  RU-TRAAK-2 is a completely reversible TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) inhibitor. RU-TRAAK-2 exerts no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2) [1]. RU-TRAAK-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Product Name Alternative :

  GW876167 hydrochloride; BVT-933 hydrochloride, GW876167; BVT-943

• UNSPSC :

  12352005

• Target :

  Potassium Channel

• Type :

  Reference compound

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/ru-traak-2.html

• Purity :

  99.53

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(NCC#CC1=CC=CC=C1)N(CC2=NC3=CC=CC=C3S2)C

• Molecular Formula :

  C19H17N3OS

• Molecular Weight :

  335.42

• References & Citations :

  [1]Su Z, et al. Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels. Proc Natl Acad Sci U S A. 2016;113 (20) :5748-5753.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1210538-56-9]