RU-TRAAK-2

• Product Name Alternative:

  GW876167 hydrochloride; BVT-933 hydrochloride, GW876167; BVT-943

• UNSPSC Description:

  RU-TRAAK-2 is a completely reversible TRAAK (TWIK-related arachidonic acid-stimulated K+ channel) inhibitor. RU-TRAAK-2 exerts no activity for non-K2P channels (Kv1.2, Slo1 and GIRK2)[1]. RU-TRAAK-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• Target Antigen:

  Potassium Channel

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/ru-traak-2.html

• Purity:

  99.72

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(NCC#CC1=CC=CC=C1)N(CC2=NC3=CC=CC=C3S2)C

• Molecular Weight:

  335.42

• References & Citations:

  [1]Su Z, et al. Novel cell-free high-throughput screening method for pharmacological tools targeting K+ channels. Proc Natl Acad Sci U S A. 2016;113(20):5748-5753.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1210538-56-9