[Ru(phen)2(4-Me-Sal)]BF4

[Ru(phen)2(4-Me-Sal)]BF4

• UNSPSC Description: [Ru(phen)2(4-Me-Sal)]BF4 (compound 10), a Ru(II)-based polypyridyl complexe, displays outstanding antiproliferative activity against drug-sensitive CCRF-CEM and multidrug-resistant CEM/ADR5000 leukemia cells (IC50=0.52 μM and 5.56 μM, respectively)[1].
• Target Antigen: Others
• Type: Reference compound
• Related Pathways: Others
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ru-phen-2-4-me-sal-bf4.html
• Solubility: 10 mM in DMSO
• Smiles: CC1=CC(O[Ru]23([N]4=C5C(C=CC6=C5[N]2=CC=C6)=CC=C4)([N]7=CC=CC8=C7C9=[N]3C=CC=C9C=C8)O=C%10)=C%10C=C1.[F-][B+3]([F-])([F-])[F-].[+]
• Molecular Weight: 683.43
• References & Citations: [1]Maryam Taghizadeh Shool, et al. Investigating the Cytotoxicity of Ru(II) Polypyridyl Complexes by Changing the Electronic Structure of Salicylaldehyde Ligands. Inorg Chem. 2023 Dec 29.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported