PROTAC ER Degrader-12

• UNSPSC Description:

  PROTAC ER Degrader-12 (Compound 70) is an estrogen receptor PROTAC degrader (DC50: 50: [1].

• Target Antigen:

  Estrogen Receptor/ERR; PROTACs

• Type:

  Reference compound

• Related Pathways:

  PROTAC;Vitamin D Related/Nuclear Receptor

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/er-degrader-8.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(C1CCC(NC1=O)=O)C2)C3=C2C=C(C=C3)N(C4)CC4(CC5)CCN5CC(CC6)CCN6C7=CC=C([C@@H]8C(C=CC(O)=C9)=C9OC[C@@H]8C%10=C(F)C=CC=C%10F)C=C7F

• Molecular Weight:

  819.91

• References & Citations:

  [1]杜武, et al. Aromatic compound, method for preparing same, and use thereof in preparation of estrogen receptor degrader. Patent WO2023241598A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported