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BAY-9683

CAT: 0804-HY-160188Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-160188Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BAY-9683 is an orally active covalent PPARG inverse agonist. BAY-9683 can be used in the study of diseases with overactive PPARG, such as luminal bladder cancer[1].
CAS Number
[2891706-83-3]
UNSPSC
12352005
Target
PPAR
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bay-9683.html
Solubility
10 mM in DMSO
Smiles
CC1=CC(N2CCOCC2)=CN=C1NC(C3=C(Cl)C=C(F)C(C(NCC4=CC=C(F)C(F)=C4)=O)=C3)=O
Molecular Formula
C25H22ClF3N4O3
Molecular Weight
518.92
References & Citations
[1]Orsi DL, et al. Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists. Bioorg Med Chem. 2023 Jan 15;78:117130.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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